Try these parameter values:
Selection For the Double-Heterozygote (AAbb)
Selection at multiple loci can have considerably more complicated dynamics than selection at one locus. However, if the loci are independent with regards to selection, then multi-locus genotype frequencies will behave the same as they would in a one-locus system. Two-locus genotype frequencies can be found, for example, by multiplying the corresponding one-locus genotype frequencies.
For example, suppose that f(AA) in the next generation was calculated to be 0.4 and f(Bb) was calculated to be 0.3. Then the frequency of the two-locus genotype, f(AABb) would be 0.4*0.3=0.12.
When the two loci are not independent of each other, complications arise (for example, linkage disequilibrium can result). See the section on linkage equilibrium for more information.
Adjust the initial allelic frequencies and the fitness values to the right:
For best results, begin by setting the fitness values to 1.0, and initial allelic frequencies to 0.5. Then, decrease one or more of the fitness values by a small amount.
The initial allelic and genotypic frequencies are displayed below the graph whereas the run-time frequencies are displayed above the graph.
In this simulaiton, two loci are subjected to independent selection pressures in a population of 5000 individuals. Because the two loci in this simulation are independent with respect to selection gene frequencies at each locus will be identical to the case of one-locus selection.Two-locus genotype frequencies can be found by multiplying the two corresponding one-locus genotype frequencies.